MARIANA BOLLO
Independent Researcher at CONICET
Associate Professor at IUCBC, Institute of Biomedical Sciences of Córdoba.
Calcium signaling under conditions of acute stress
The research line of Dr. Mariana Bollo focuses on cellular protective responses activated under conditions of acute stress, with particular emphasis on the role of calcium signaling in the restoration of normal cellular function. In addition, pathological aspects associated with these responses are examined.
Current research activities are organized around three main lines:
- Cellular protective mechanisms triggered by endoplasmic reticulum stress in astrocytes during inflammatory processes.
- The role of endoplasmic reticulum stress activation in cell death mechanisms in a neurodegenerative gangliosidosis model (Tay-Sachs and Sandhoff diseases).
Long-term goal: to develop a therapeutic strategy for patients with GLUT-1 deficiency (GLUT-1 DS), based on the evaluation of a compound that increases mitochondrial Ca2+ levels in astrocytes, enhances ATP production, and significantly reduces neuroinflammation.
CONTACT
Email: mbollo@immf.uncor.edu
Social network: 
PROFESSIONAL BACKGROUND
Education
2003–2007: NIH Postdoctoral Fellowship, Department of Physiology, Health Science Center at San Antonio, University of Texas, USA.
1998–2002: PhD in Biological Sciences, Department of Molecular Biology, National University of Río Cuarto (UNRC). Doctoral Fellowships from CONICOR and CONICET.
1991–1996: Degree in Microbiology, National University of Río Cuarto (UNRC).
Positions Held
2008–Present: Associate Researcher, IMMF/INIMEC–CONICET–UNC, Córdoba, Argentina.
2021–Present: Independent Researcher, IMMF/INIMEC–CONICET–UNC, Córdoba, Argentina.
2014–Present: Associate Professor of Biochemistry, Instituto Universitario de Ciencias Biomédicas de Córdoba (IUCBC), Córdoba, Argentina.
2013–Present: Affiliated Researcher, Department of Cellular Systems and Anatomy, Health Science Center at San Antonio, University of Texas, USA (UTHSCSA).
