Our current research line focuses on the effects of alterations of the serotonergic system during embryonic development, which could generate phenotypes related to various psychiatric and developmental disorders, such as autism, anxiety and alcohol abuse, among others.
COMPETITIVE RESEARCH FUNDS
- 2022. PICT-2021-CAT-II-00073. – «Una Salud: Un abordaje integrador para el estudio de endoparasitosis y malnutrición en la provincia de Córdoba» Member of the group.
- 2022-2023. PIBAA. CONICET “Análisis del rol de alteraciones del sistema serotoninérgico durante la embriogénesis en el desarrollo de conductas de tipo ansiosa, depresiva y déficits sociales”. PI.
- 2023-2025. Proyecto PIP CONICET. “Neuroinflamación condicionada y factores moduladores del consumo episódico elevado de alcohol en adolescencia”. GR.
- 2022-2023. PICT 2020 SERIE A-02753 “Alteraciones en el sistema serotoninérgico durante periodos sensibles del desarrollo y su participación en el desarrollo de conductas problemáticas y déficits sociales” PI.
PUBLICATIONS (LATEST FIVE YEARS)
- Salguero A, Barey A, Virgolini RG, Mujica V, Fabio MC, Miranda-Morales RS, Marengo L, Camarini R, Pautassi RM. Juvenile variable stress modulates, in female but not in male Wistar rats, ethanol intake in adulthood. Neurotoxicol Teratol. 2023 Oct 4;100:107306. doi: 10.1016/j.ntt.2023.107306.
- Marengo L, Fabio MC, Bernal IS, Salguero A, Molina JC, Morón I, Cendán CM, D’Addario C, Pautassi RM. Folate administration ameliorates neurobehavioral effects of prenatal ethanol exposure. Am J Drug Alcohol Abuse. 2023 Jan 2;49(1):63-75. doi: 10.1080/00952990.2022.2159425.
- Leyva LR, Salguero A, Virgolini MB, Romero VL, Marengo L, Fabio MC, Morón I, Cendán CM, Pautassi RM. Binge eating promotes ethanol self-administration in female rats with a history of intermittent ethanol exposure at adolescence. Drug Alcohol Depend. 2023 Feb 1;243:109737. doi: 10.1016/j.drugalcdep.2022.109737.
- Fabio, MC; Servin-Bernal, I; Degano, AL; Pautassi, RM. “Serotonin disruption at gestation alters expression of genes associated with serotonin synthesis and reuptake at weaning”. PSYCHOPHARMACOLOGY, (2022). doi 10.1007/s00213-022-06228-z
- Pautassi, R.M. & Fabio, M.C. 2022 A double- hit model reveals individual and synergic consequences of prenatal and adolescent postnatal ethanol exposure. Alcoholism: Clinical and Experimental Research, 00, 1– 3. A
- Pautassi RM, Wille-Bille A, Fernandez MS, Fabio MC 2023. Ethanol Intake on Preclinical Models: Methods of Assessment and Effects on Dopamine Signaling. En: Fuentealba-Evans, J.A., Henny, P. (eds) Dopaminergic System Function and Dysfunction: Experimental Approaches. Neuromethods, vol 193 pps. 163-181 Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2799-0_8. ISBN 978-1-0716-2798-3
- Marengo L, Fabio MC, Servin-Bernal I, Salguero A, Molina JC, Moron-Henche I, Cendán CM, D’Addario C, Pautassi RM. Folate Administration Ameliorates Neurobehavioral Effects Of Prenatal Ethanol Exposure. 2023. The American Journal of Drug and Alcohol Abuse. Feb 1;1-13. doi: 10.1080/00952990.2022.2159425.
- Ruiz-Leyva L, Salguero A, Virgolini M, Romero VL, Marengo L, Fabio MC, Morón Henche I, Cendán CM, Pautassi RM. Binge eating promotes ethanol self-administration in female rats with a history of intermittent ethanol exposure at adolescence. Drug and Alcohol Dependence.
- ZALOSNIK MI, FABIO MC, BERTOLDI, ML, CASTAÑARES CN DEGANO AL. 2021. MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge. Scientific Reports.: Nature Research. vol.11 n°1. eissn 2045-2322
- Bellia F, Suarez A, D’Addario C, Pautassi, RM; Fabio MC. «Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice». PSYCHOPHARMACOLOGY, 2021. doi: 10.1007/s00213-020-05670-1.
- Suarez A, Fabio MC, Bellia F, Fernández MS, Pautassi RM 2020 Environmental enrichment during adolescence heightens ethanol intake in female , but not male , adolescent rats that are selectively bred for high and low ethanol intake during adolescence Environmental enrichment during adolescence heightens ethanol inta. 00:0–12. https://doi.org/10.1080/00952990.2020.1770778
- Complete and updated list available here.
TEAM
